Nucleosides and Analogues
Medchemexpress LLC 2'-Deoxyguanosine-d13 | 961-07-9 | 99.9% | 280.32 | 5 MG
2'-Deoxyguanosine-d13 is a deuterium-labeled version of 2'-Deoxyguanosine. It is intended for research use only and can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC N6-Threonylcarbamoyladenosine | 24719-82-2 | 99.6% | 412.35 | 1 MG
N6-Threonylcarbamoyladenosine is a common nucleoside that can decorate and become tRNA. It is for research use only.
- Purity of 99.62%
- Molecular weight of 412.35
- Chemical formula: C15H20N6O8
- Appearance: Solid
- Color: Off-white to light brown
- Storage conditions: -20°C for powder, -80°C for 6 months in solvent
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 25mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dilithium) | 1927-31-7 | 99.2% | 517.94 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dATP-13C10,15N5) dilithium is a 13C and 15N-labeled nucleotide essential for DNA synthesis as a substrate of DNA polymerase. It is valuable in research as:
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-d14 (dilithium) (dATP-d14 (dilithium)) | 2687960-68-3 | 97.10% | 517.13 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-d14 (dATP-d14) dilithium is deuterium labeled 2'-Deoxyadenosine-5'-triphosphate. It is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium | 1927-31-7 | 95.0% | 512.97 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium (dATP-13C10 dilithium) is a 13C-labeled version of 2'-Deoxyadenosine-5'-triphosphate (dATP). dATP is a nucleotide crucial for DNA synthesis or replication in cells, serving as a substrate for DNA polymerase.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Suitable for analysis by NMR
- Suitable for analysis by GC-MS
- Suitable for analysis by LC-MS
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 1g
A nucleoside building block; has been used in the synthesis of various oligonucleotides
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 251.24 g/mol | C10H13N5O3 | 500 MG
2'-deoxyadenosine is an adenine nucleoside supplied for research and analytical applications. The compound has been reported to inhibit glucose-stimulated insulin release, activate caspase-3 and promote apoptosis, and inhibit S-adenosyl-L-homocysteine hydrolase (SAHH).
- Adenine nucleoside for research applications.
- Modulates insulin-stimulated cAMP accumulation and insulin release.
- Promotes apoptosis via caspase-3 activation.
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH).
- Available from suppliers in small research quantities (supplier pack indicated as 500 MG in provided row data).
Chem-Impex International, Inc. 2'-Deoxyguanosine monohydrate | 961-07-9 | MFCD00150760 | 5G
2'-Deoxyguanosine monohydrate, 961-07-9, MFCD00150760, 5G
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxyguanosine monohydrate 99-100% | 312693-72-4 | MFCD00150760 | 25MG
2'-Deoxyguanosine monohydrate 99-100% | Purity: 99-100% | Mol Wt: 285.26 | 312693-72-4 | MFCD00150760 | 25MG
Biotium Primary Antibody CA15 3 CD227 EMA MUC1 VU-4H5 CF740 1/EA
MAb VU-4H5 reacts with MUC1 a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia The dominant epitope of MAb VU4H5 is APDTR as established with epitope fingerprinting VU-4H5 preferentially binds to under-glycosylated tumor MUC1 The extracellular domain of MUC1 largely consists of a highly conserved O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (15N5 98%) CP 95% 1 mg
8-Hydroxy-2-deoxyguanosine (15N5 98%) CP 95% 1 mg
Medchemexpress LLC 6-Thio-2'-deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This compound has shown rapid cell death in various cancer cell lines with IC50 values between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreased tumor growth rate, outperforming 6-thioguanine treatment, and increased telomere dysfunction in tumor cells in vivo. It is for research use only.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in various cancer cell lines
- Decreases tumor growth rate in mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo